Category Archives: free radicals

Another Cocoa Study Shows Positive Effects on Hypertension

Here’s a study from The Journal of the American Medical Association that shows that cocoa, or more specifically, the polyphenols in cocoa, has a positive effect on blood pressure. It points out several important facts:

  • It doesn’t need to be a huge quantity of dark chocolate to have an effect
  • The dark chocolate must be taken regularly
  • It must be taken on an ongoing basis

The study was performed on a rather small population (44 individuals) with untreated prehypertension (120-139/80-89) or stage 1 hypertension (140-159/90-99) without any other risk factors. According to the study, the prevalence of hypertension decreased from 86% to 68%. The participants were given either 6.3 g of dark chocolate containing 30 mg of polyphenols or the same amount of white chocolate which contained no polyphenols for a period of 18 weeks.

The study also points out that blood nitric oxide levels increased in the test participants. Nitric oxide is what triggers the dilation of the blood vessels and reduces blood pressure.

Here’s the link to the abstract of the study:

JAMA — Abstract: Effects of Low Habitual Cocoa Intake on Blood Pressure and Bioactive Nitric Oxide: A Randomized Controlled Trial, July 4, 2007, Taubert et al. 298 (1): 49

In my opinion, the thing about eating chocolate as a “medicine” is that healthy individuals probably wouldn’t feel any different, even though the polyphenols would be of benefit. Individuals with cardiovascular disease could probably measure an improvement and may feel healthier.

I know that has been the case with me.

A Plethora of Antioxidant Acronyms

If you’re like me, you might feel like you’ve been dropped in a vat of alphabet soup when you read about anti-aging or antioxidants. I’m no microbiologist or even a whiz at word games, but I’ll give a shot at trying to ‘splain some of the acronyms involved in the articles about which I post.

Since many of the articles refer to free radicals along with the acronyms, I’ll start off by trying to explain free radicals. High school chemistry was a very long time ago, but I seem to remember that there are some molecules that are short an electron – have an odd number, or whose valance (outer shell) is not full. These molecules seek to fill that outer shell by either sharing an electron or by “stealing” some from another molecule. Many metals are such molecules, as is oxygen. That’s why oxygen is expressed as O2. Two oxygen atoms bond together by sharing electrons to fill their outer electron shell. We all know that oxygen will react with metal to create rust. That is oxygen combining with the metals to fill the outer shell.

Here’s an article that explains chemical bonding far better than I can.
http://www.school-for-champions.com/chemistry/bonding.htm

In our bodies, we need oxygen to fuel cellular energy production, but at the same time, oxygen and other reactive molecules can interact with with cell membranes or even DNA. Our cells can fail to function properly or die prematurely due to such damage. Cholesterol can also oxidize, which contributes to the buildup of plaque in our circulatory system. Luckily, our bodies have a defense against this type of damage. We have some enzymes that scavenge the molecules that need extra electrons & “loan” them some. However, many other free radical fighters are contained in food. These “antioxidants” can bond with the free radicals and prevent or minimize cellular damage.

Besides normal metabolism, there are many environmental factors that increase the amount of free radicals in our bodies, such as:

  • stress
  • smoking
  • pollution
  • sun overexposure
  • radiation

My next post will dive into some acronyms.

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